Acute pulmonary embolism: devices and trials supporting endovascular intervention

Jorinde Van Laanen is pleased to interview Makis Avgerinos about acute pulmonary embolism. She asks him about the devices available for endovascular interventions to treat this disease, and he shares his expertise by detailing the benefits of each in very specific situations.

Then, they discuss the type of evidence needed to accept endovascular intervention for pulmonary embolism as a first-line treatment, mentioning two key trials: HI-PEITHO, which compares ultrasound-facilitated, catheter-directed thrombolysis with anticoagulation alone for intermediate-high risk acute pulmonary embolism, and PEERLESS II, a study on the FlowTriever system plus anticoagulation compared with anticoagulation alone for intermediate risk acute pulmonary embolism.