Writing the carotid chapter: Prof. Schneider and Dr. Lareyre on the new PVI Trials Book

Dr. Fabien Lareyre connects with Prof. Peter Schneider to discuss carotid disease, CLTI, and the dedicated carotid chapter of the yearly updated PVI Trials Book, the essential reference for the most influential vascular studies.

Prof. Schneider introduces the 2025 carotid chapter, which covers both symptomatic and asymptomatic carotid disease, emerging technologies, and new topics such as cryptogenic stroke. 

He reviews established trials like ACST-2 and highlights growing evidence on the association between asymptomatic carotid stenosis and cognitive decline, an increasingly discussed clinical issue.

Looking ahead, Prof. Schneider identifies CREST-2 as the landmark trial to watch: reporting in 2026, it could reshape guideline recommendations regardless of its final outcome. 
The interview also explores the expanding role of artificial intelligence in carotid care, from imaging analysis to plaque characterisation and fundamental research.

Download the 2024 edition of the PVI Trials Book now to get the full context behind the trials discussed, and stay ready for the updated 2025 edition!