Sex differences in peripheral vascular disease: a scientific statement from the American Heart Association

Selected in Circulation by Hortense Chalret du Rieu

This AHA scientific statement reviews sex-based differences and disparities in peripheral arterial disease (PAD), highlighting significant variations in epidemiology, risk factors, diagnostic approaches, treatment strategies, and clinical outcomes. The paper also outlines key priorities to guide future research and improve equity in care delivery.

References:

Authors: Esther S.H. Kim, Shipra Arya, Yolanda Bryce, Heather L. Gornik, Chandler A. Long, Mary M. McDermott, Amy West Pollak, Vincent Lopez Rowe, Alexander E. Sullivan, and Mary O. Whipple, on behalf of the American Heart Association Council on Peripheral Vascular Disease; Council on Cardiovascular and Stroke Nursing; Council on Clinical Cardiology; Council on Genomic and Precision Medicine; Council on Quality of Care and Outcomes Research; and Stroke Council

Reference: Circulation Volume 151, Number 14 - Originally Published 11 March 2025

DOI: 10.1161/CIR.0000000000001310

Read the abstract

Objective:

The objective was to report sex-based differences in PAD and to provide priorities to mitigate sex-related disparities.

Study:

AHA scientific statements.

Outcomes and conclusion:

Significant sex-based differences and disparities in epidemiology, risk factors, diagnosis, treatment, and outcomes of PVD.

Sex differences in peripheral vascular disease

Sex differences in PVD. Source: Circulation