Late-breaking trials: new evidence shaping revascularisation in limb ischemia

This PVI 2025 late-breaking trials session brings together pivotal data addressing some of the most pressing questions in limb ischemia management. 

From rotational mechanical athero-thrombectomy in acute and subacute ischemia to real-world outcomes of transcatheter arterialisation of the deep veins in no-option CLTI, the presentations explore efficacy, safety, durability, and long-term outcomes across a broad spectrum of techniques. 

High ischemic-risk limb presentation is examined through post hoc REVIVE data, while multiple analyses focus on drug-coated and drug-eluting technologies, clarifying their long-term performance, survival impact, and role versus bare-metal or plain balloon strategies. 

Together, these studies provide a comprehensive, evidence-based update on how contemporary endovascular and surgical approaches are reshaping outcomes in complex PAD and CLTI populations.